What is Mesothelioma?
Mesothelioma, also known as asbestos cancer,
is a rare but deadly disease which affects the pleura (a thin lining
surrounding the lungs) and other parts of the body. It is caused by
exposure to asbestos, naturally occurring minerals which were widely
used in various industries for their fire-resistant properties. The most
common form of this cancer is lung mesothelioma, which is also known as
pleural mesothelioma. Asbestos fibers can also attack the lining of the
abdominal cavity, resulting in peritoneal mesothelioma. Additionally, mesothelioma cancer sometimes affects the pericardium, a sac which surrounds the heart, as well as other organs in the body.
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How Does Mesothelioma Develop?
The
development of mesothelioma is a drawn-out process, which makes it hard
to diagnose and treat. On average, it takes decades for the symptoms of mesothelioma
to surface. Mesothelioma can mask its presence because its symptoms
resemble those of more common respiratory illnesses. By the time a
doctor orders a battery of tests to look for mesothelioma, it is usually
too late to treat the cancer effectively. Symptoms include shortness of
breath, chest pains, or a combination of both. As mesothelioma advances
to its final stage, symptoms can become more severe and typically
include severe chest and lung pain, bloating, coughing up blood,
difficulty in swallowing, or buildup of fluid in the chest cavity.
Extreme tiredness, lack of appetite, and subsequent weight loss, skin
rashes, nausea, vomiting, abdominal pain, night sweats, and fever.
Between 2,000 to 3,000 new cases of mesothelioma are diagnosed in the U.S. every year.
Who Is the Average Mesothelioma Patient?
The
majority of mesothelioma victims are people who have been in the armed
forces and/or worked in an environment in which they were in daily
contact with asbestos.
A case in point: U.S. Navy ships of all
types that were launched and saw service from the 1930s to the early
1960s contained extremely large amounts of asbestos. Decks,
compartment walls, hulls, electrical systems, steam pipes, and more
contain asbestos fibers in order to add tensile strength, resistance to
fire and heat, and low electrical conductivity. This made ships safer,
particularly in regards to extreme temperatures and fires. However,
these large amounts of asbestos containing materials present in warships
and auxiliary vessels exposed sailors, Marines, and repair yard workers
to carcinogenic asbestos fibers which trigger the disease.
In the
civilian economy, many worksites such as electrical plants, steel
mills, manufacturing facilities, oil refineries, welding businesses, and
more used asbestos extensively prior to its ban. Prior to its ban in
the late 20th Century, asbestos was used in many industrial plants, port
facilities, and other buildings across the world where millions of
workers were regularly exposed to it during their workdays.
Many
owners of enterprises where fire and/or high temperatures are used in
the manufacturing process used large amounts of asbestos to make their
production facilities safer and more efficient. Asbestos was added to
many factory components to make them stronger and able to resist flame
and extreme heat. While these measures had positive results in
preventing fires or diminishing the damage from them, they also exposed
many industrial workers to asbestos fibers.
Although anyone
exposed to asbestos is at some risk of developing mesothelioma, the
average patients of this asbestos-related malady are usually males. This
is because males were the predominant gender in the armed forces or in
work sites which asbestos was used prior to its ban. Since it usually
takes between 10 and 50 years from the initial exposure to a definitive
diagnosis, mesothelioma patients are commonly older men in the 60-70 age
group.
How Doctors Diagnose Mesothelioma
Unfortunately,
as previously stated, it takes sometimes up to 50 years in order for
doctors to diagnose mesothelioma since the symptoms tend to show up
slowly. Even then, the symptoms manifest themselves so subtly that
unless a physician has a patient’s complete medical and work history,
including the fact that he or she was exposed to asbestos, diagnosis may
be delayed.
Once a doctor begins the process of obtaining a
diagnosis, several blood tests, CT scans, chest X-rays and a biopsy are
usually performed. A biopsy allows the doctor to remove bits of lung
tissue in order to search for asbestos fibers or indications of lesions
or tumors. If a patient is diagnosed with mesothelioma, his or her
physician will be also be able to assess what stage of the disease has
reached.
The Four Stages of Mesothelioma
Mesothelioma has
four stages. The first stage is the earliest of the disease where the
mesothelioma tumor is not fully formed. Patients with stage Ia and Ib
mesothelioma have the best chances of getting the cancerous cells
removed. As the mesothelioma tumors grow and affect more healthy tissue,
the stage number rises, with Stage IV being the final stage. Stage II
of mesothelioma still renders hope for the patient since the tumor,
although it has increased in size, still has not spread to the point in
which surgery is not an option.
Once a patient reaches Stage III,
the cancer has moved to adjacent parts of the body and a patient’s life
expectancy is shorter when compared to that when the cancer is in Stages
I and II. However, if the tumor is in mass, surgery may still be an
option for certain patients. However, once mesothelioma reaches Stage
IV, the prognosis is not a good one and physicians will search for
palliative treatments instead of treatments that promise a cure.
Palliative treatments focus on helping mesothelioma patients manage pain
and prolong their lives instead of attempting to remove the tumors. In
the majority of cases, the tumors are far too widespread during this
stage to be surgically removed.
The four stages of mesothelioma are listed and defined below:
- Stage Ia: Tumor is in the outer layer of the pleura (parietal pleura). It is not in the pleura covering the lung (visceral pleura).
- Stage Ib: Tumor is in both the parietal and visceral pleura
- Stage II: Tumor has spread into the lung or diaphragm.
- Stage III: Tumor has spread to one or more of these organs or areas: the pericardium, part of the chest wall, or lymph glands inside the chest
- Stage IV: Tumor has metastasized to one or more of the following: across the chest wall or pericardium, various areas of the chest wall, the heart, liver, windpipe or esophagus, or the opposite lung.
Unfortunately,
many individuals may not even know they have mesothelioma until they
have been diagnosed. Some patients’ mesothelioma tumors are not found
until they’re reached Stage IV since it takes decades from the initial
exposure to asbestos for the first symptoms to manifest themselves.
Mesothelioma Treatments
Chemotherapy,
radiation, or a combination of both are the most effective forms of
mesothelioma treatments currently available. However, if the disease is
detected in Stages Ia or Ib, surgery is almost always recommended in
order to remove the tumor. The caveat, of course, is that the patient
must meet certain health and age requirements. Older patients and/or
patients with less-than-ideal health conditions may not be able to
withstand the physical demands of a surgical procedure.
If the cancer has reached its late stages, especially Stage IV, multimodal treatment options
are used. Multimodal treatment is a combination of two different types
of treatments, typically chemotherapy and radiation. Surgery is not a
widely-used option for patients with Stages III and IV mesothelioma,
since the poor state of health of the patient, as well as the possible
metastasis of the tumor makes surgery extremely risky.
In addition
to standard treatments, many mesothelioma patients have chosen a wide
variety of complementary or alternative treatments. Herbal therapies
which involve the use of herbs and vitamins, acupuncture, holistic
healing, meditation, and yoga are a fraction of the alternative
treatments that can be employed against mesothelioma. Although many
alternative treatments are not recognized in traditional medical
practices, many doctors and healthcare practitioners are more accepting
and open minded of how effective these non-traditional treatments can
be. As a result of their willingness to embrace new ideas, some of these
enterprising doctors have opened up their own alternative medicine
practice.